NYU Data Catalog

NYU Dataset

Authors: Juan Rivera-Correa

Joseph Verdi

Julian Sherman

Jeremy M. Sternberg

2 more author(s)...
Description: Anemia is a common complication in many infectious diseases, including protozoan parasitic infections. Trypanosomes are eukaryotic parasites and most relevant human trypanosome pathogens are Trypanosoma brucei and Trypanosoma cruzi. Autoimmunity during Trypanosoma brucei infection is indicated to have a role during anemia, but anemia caused by trypanosome infection is poorly understood. In mouse models...
Subject: Infectious Disease
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NYU Dataset

Authors: Akash G. Patel

Pramod N. Nehete

Sara R. Krivoshik

Xuewei Pei

7 more author(s)...
Description: Previous studies showed that harnessing innate immunity via CpG oligodeoxynucleotides (ODNs) modulates age-related defects. This study used elderly female squirrel monkeys as model of sporadic Alzheimer’s disease pathology. Current immunotherapeutic trials for Alzheimer’s disease have amyloid-related imaging flaws, which are linked to the presence of cerebral amyloid angiopathy (CAA). Therefore, the...
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NYU Dataset

Authors: Carla Nasca

Josh Dobbin

Benedetta Bigio

Kathleen Watson

9 more author(s)...
Description: Previous studies in rodent showed impaired brain insulin signaling with resultant insulin resistance (IR) modulates synaptic plasticity and the corresponding behavioral functions. This study investigated whether brain enriched exosomes and brain IR differ between subjects with major depressive disorder (MDD) and respective controls. They also examined potential sex differences in circulating brain...
Subject: Neuroscience
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NYU Dataset

Authors: Claudia Gomes

Marisol Zuniga

Kelly A. Crotty

Kun Qian

11 more author(s)...
Description: This is a retrospective cohort study of COVID-19 hospitalized patients with different degrees of severity. They performed this study to analyze the generation of autoimmune antibodies to common antigens. This study included 115 hospitalized patients with SARS-CoV-2 infection and 42 uninfected controls. Sample collection was performed as part of routine clinical care for COVID-19 patients at the time...
Subject: COVID-19

Infectious Disease
Timeframe: 2020
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NYU Dataset

Authors: Marisol Zuniga

Claudia Gomes

Steven E. Carsons

Michael T. Bender

4 more author(s)...
Description: This study examined autoimmune antibodies to annexin A2, which is a phospholipid-binding protein expressed in the lung and other organs, in COVID-19 patients. Annexin A2 is critical for fibrinolysis, lung elasticity, cell membrane repair, and integrity of the pulmonary vasculature. Therefore, antagonism of annexin A2 may explain many of the clinical features of severe COVID-19 cases. This study analyzed...
Subject: COVID-19

Infectious Disease
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NYU Dataset

Authors: Ibrahim T. Mughrabi

Jordan Hickman

Naveen Jayaprakash

Dane Thompson

13 more author(s)...
Description: This study developed a scalable model for long-term vagus nerve stimulation (VNS) in mice. For this study, C57BL/6 mice were used in all experiments. The dataset includes histology and immunohistochemistry data as well as supplementary data tied to the publication. The supplementary data includes data that was used to assemble different figures in the publication, which contains data about heart rate...
Subject: Neuroscience
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